RNA N-glycosylation enables immune evasion and homeostatic efferocytosis

Nature
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Nature, Published online: 06 August 2025; doi:10.1038/s41586-025-09310-6

N-glycans on glycoRNAs prevent innate immune sensing of endogenous small RNAs, and the natural mechanism they use demonstrates how glycoRNAs exist on the cell surface and in the endosomal network without inducing autoinflammatory responses.
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