Foreign ministers condemn strikes amid fears of wider war, but reaction from Iran’s proxies is relatively measured

• Middle East crisis – live updates

Nations across the Middle East condemned the Israeli strikes on Iran on Friday, calling for urgent de-escalation amid concerns that tit-for-tat retaliation could lead to a wider war with regional fallout.

Israel’s carried out hundreds of strikes across Iran, killing top military and nuclear officials and targeting nuclear facilities – the most serious Israeli attack on Iran ever. Iran responded by launching at least 100 drones and ballistic missiles in Israel’s direction, most of which were shot down, according to the Israeli military. Iran has vowed revenge, with the country’s supreme leader Ayatollah Ali Khamenei threatening “severe punishment.”